Publications

  1. GM-CSF receptor expression determines opposing innate memory phenotypes at different stages of myelopoiesis. Guerrero P, Bono C, Sobén M, Guiu A, Cheng QJ, Gil ML, Yáñez A. Blood 2024. PMID: 38603633.
  2. Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks. Cheng, Q.J., Farrell, K., Fenn, J., Ma, Z., Makanani, S., Siemsen, J. Sci Rep, 2024. PMID: 38228717.
  3. Tonic TNF conditioning of macrophages safeguards stimulus-specific inflammatory responses. Luecke S, Adelaja A, Guo X, Sen S, Spreafico R, Singh A, Liu Y, Taylor B, Diaz J, Cheng Q, Hoffmann A. EMBO Reports, 2023. PMID 37212045.
  4. A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes. Wilder CL, Lefaudeux D, Mathenge R, Kishimoto K, Zuniga Munoz A, Nguyen MA, Meyer AS, Cheng QJ, Hoffmann A. Mol Syst Bio, 2023. PMID 36929731.
  5. Stochastic models of nucleosome dynamics reveal regulatory rules of stimulus-induced epigenome remodeling. J Kim, KS Sheu, QJ Cheng, A Hoffmann, G Enciso. Cell Reports, 2022. PMID 35830792.
  6. NFκB dynamics determine the stimulus-specificity of epigenomic reprogramming in macrophages. QJ Cheng, S Ohta, KS Sheu, R Spreafico, A Adelaja, B Taylor, A Hoffmann. Science, 2021. PMID 34140389.
  7. High dose IFN-β activates GAF to enhance expression of ISGF3 target genes in MLE12 epithelial cells. K Kishimoto, CL Wilder, J Buchanan, M Nguyen, C Okeke, A Hoffmann, QJ Cheng. Frontiers in Immunology, 2021. PMID 33897699.
  8. An NFκB activity calculator to delineate signaling crosstalk: type I and type II interferon modulate NFκB signaling via distinct mechanisms. S Mitchell, EL Mercado, A Adelaja, J Ho, QJ Cheng, G Ghosh, A Hoffmann. Frontiers in Immunology, 2019. PMID 31293585.
  9. Sequential conditioning-stimulation reveals distinct gene- and stimulus-specific effects of Type I and II IFN on human macrophage functions. Q Cheng, F Behzadi, S Sen, S Ohta, R Spreafico, R Teles, R Modlin, A Hoffmann. Scientific Reports, 2019. PMID 30918279.
  10. Duodenoscope-related outbreak of a carbapenem-resistant Klebsiella pneumoniae identified using advanced molecular diagnostics. RM Humphries, S Yang, S Kim, VR Muthusamy, D Russell, A Trout, T Zaroda, QJ Cheng, G Aldrovandi, DZ Uslan, P Hemarajata, Z Rubin. Clin Infect Dis. 2017. PMID 29579235.
  11. Probing chromatin landscape reveals roles of endocardial TBX20 in septation. CJ Boogerd, I Aneas, N Sakabe, RJ Dirschinger, QJ Cheng, B Zhou, J Chen, MA Nobrega, SM Evans. J Clin Invest. 2016. PMID 27348591.
  12. Who provides primary care? An assessment of HIV patient and provider practices and preferences. QJ Cheng, EM Engelage, TR Grogan, JS Currier, RM Hoffman. J AIDS Clin Res. 2014. PMID 25914854.
  13. Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana. S Kashiwagi, I Kuraoka, Y Fujiwara, K Hitomi, QJ Cheng, JO Fuss, DS Shin, C Masutani, JA Tainer, F Hanaoka, S Iwai. J. Nucleic Acids 2010. PMID 20936172.
  14. XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations. L Fan, JO Fuss, QJ Cheng, AS Arvai, M Hammel, VA Roberts, PK Cooper, JA Tainer. Cell 2008. PMID 18510924.